2. 2. 1. Limits for carcinogenic, mutagenic and reprotoxic substances (CMR substances)

description relevant product categories 


According to Directives 67/548/EEC and 1999/45/EC, respectively, CMR substances are defined as follows:

These definitions of CMR substances largely correspond with those given in the CLP Regulation (Regulation (EC) No 1272/2008). However, the Regulation uses the term "mixture" instead of the term "preparation", which has been used in previous legislation.

minimum requirement

Substances which have been classified as carcinogenic, mutagenic or reprotoxic in Directive 67/548/EEC or in the CLP Regulation 1272/2008, respectively (see table) must not exceed the following percentages (m/m) in chemicals and products:


Directive 67/548/EEC

(Annex VI) 

CLP Regulation

1272/2008 (Annex I) 



Categories 1,2: R45, R49

Category 3: R40


Categories 1A, 1B: H350, H350i

Category 2: H351


≤ 0,1

≤ 1


Categories 1,2: R46

Category 3: R68

Germ cell mutagenicity

Categories 1A, 1B: H340

Category 2: H341


≤ 0,1

≤ 1

Toxic to reproduction 

Categories 1,2: R60 or R61

Category 3: R62, R63

Reproductive toxicity

Categories 1A, 1B: H360

Category 2: H361


≤ 0,1

≤ 1

Addition: Lactation:   


Reproductive toxicity:

Adverse  effects on or via lactation: H362


≤ 1


Supporting documents:
Safety data sheet in accordance with Regulation (EC) No 1907/2006 as amended by Regulation (EU) No 453/2010.


All products bearing one of the following organic labels meet these criteria:

Alternatively, the corresponding baubook declaration may serve as evidence (www.baubook.info/oea).

background, sources
Weiterführende Informationen

baubook green procurement
Harmonised “EcoBuildingCriteria” provided by “ÖkoKauf Wien” and “service package sustainable construction in Vorarlberg”